The Thermalist® Journal

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What Too Much Wheat Is Causing to Your Metabolism
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What Too Much Wheat Is Causing to Your Metabolism

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Dr. Susanna Søberg's avatar
Dr. Susanna Søberg
Apr 25, 2025
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The Thermalist® Journal
What Too Much Wheat Is Causing to Your Metabolism
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Humans naturally consume carbohydrates as part of their daily diet. One of the most commonly consumed sources of carbohydrates is wheat in its various forms, such as bread, pasta, and baked goods. However, what many people do not realize is that consuming too much wheat can have detrimental effects on our metabolism.

Today, we will examine how excessive wheat consumption can impact metabolism and ultimately affect overall health. Let's explore the science behind it and understand why moderation is key in incorporating wheat into our diets.

Shall we?

Wheat and its Effects on Metabolism

Before we discuss the specifics, let's first understand metabolism. Metabolism refers to the chemical processes in our body that convert food into energy. It is vital for maintaining overall health and crucial to weight management.

Now, let's talk about wheat—one of the most commonly consumed grains worldwide. Wheat contains gluten, a protein that gives bread its elastic texture and helps it rise. Gluten also acts as a binding agent in many processed foods.

When consumed in moderation, wheat can be a nutritious addition to our diet as it is rich in fiber, vitamins, and minerals. However, excessive consumption of wheat has been linked to various health issues, including:

Metabolic Syndrome

Metabolic syndrome is a cluster of conditions—including elevated blood pressure, dyslipidemia, insulin resistance, and central obesity—that collectively increase the risk of cardiovascular disease and type 2 diabetes.

A study by A. Esmaillzadeh and colleagues investigated the relationship between whole-grain consumption, refined-grain intake, and metabolic syndrome in Tehranian adults, revealing significant dietary influences on metabolic health.

This cross-sectional study evaluated associations between whole-grain and refined-grain intake, metabolic syndrome, and risk factors in 827 adults (357 men, 470 women) aged 18–74 years in Tehran, Iran.

Dietary assessment was conducted using food frequency questionnaires, with grain products classified as whole or refined using the Jacobs et al. methodology. Clinical measurements included calculating body mass index (BMI) from standardized height and weight measurements. Fasting blood samples assessed lipid profiles, glucose levels, and blood pressure.

Metabolic syndrome and lipid abnormalities were defined using Adult Treatment Panel III guidelines. Hypertension was classified per the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.

Diabetes diagnosis required fasting plasma glucose ≥126 mg/dL or post-challenge glucose ≥200 mg/dL. For comparative analysis, participants were stratified into quartiles based on whole- and refined-grain intake.

The mean daily intake was 93 ± 29 grams for whole grains and 201 ± 57 grams for refined grains, with both genders consuming more refined grains. Higher whole-grain intake correlated with reduced risks of metabolic syndrome components.

Specifically, the risk of hypertriglyceridemia, hypertension, and metabolic syndrome decreased across increasing quartiles of whole-grain consumption. Conversely, higher refined-grain intake was associated with increased risks of hypercholesterolemia, hypertriglyceridemia, hypertension, and metabolic syndrome.

Whole-grain consumption demonstrated a protective, dose-dependent association against metabolic syndrome and its components, while refined-grain intake significantly increased risks. The study underscores the importance of incorporating whole grains into a healthy diet for overall metabolic health.


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